consensus accuracy

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Advancements in Secondary Analysis for Variant Calling

Thydian Windsor, a Research Scientist in the Machine Learning team at Oxford Nanopore Technologies, gave the secondary analysis update at the Nanopore Community Meeting. They defined secondary analysis as “what does the collection of reads say in aggregate?” For variant calling, improvements on the base-calling side with base-calling models and motor enzymes have been released. […]
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Advancements in Bacterial and Plasmid Sequencing Techniques

Katherine Lawrence, from the Machine Learning and Bioinformatics team at Oxford Nanopore Technologies, spoke at the Nanopore Community Meeting on “Bacterial isolate and plasmid sequencing.” Lawrence began by emphasizing the importance of microbes and learning about their sequences. Long reads help assemble bacterial genomes efficiently. Bacterial genome modifications include 4mC, 5mC, and 6mA. Lawrence noted […]
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2023 Dorado Updates

Joyjit Daw, a Principal Machine Learning Engineer at Oxford Nanopore Technologies (ONT), provided a Dorado update at the Nanopore Community Meeting Houston meeting. The Dorado v0.5.0 release supports core Guppy features, custom barcodes, read splitting, and Minimap2 alignment. Dorado has been integrated into MinKNOW. They have also extended features such as hemi methylation for the […]
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Raw Read Accuracies and Genome Assembly

Alexander Wittenberg from KeyGene in the Netherlands presented at the Nanopore Community Meeting 2021 on “Accuracy improvements in crop genome assembly using the Q20+ chemistry.” They presented on improvements in sequencing and crop assembly using Q20+ chemistry. KeyGene is using genome assembly and the early access ONT program to identify pan-genome and variants. KeyGene has […]
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