mitochondrial DNA

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Sequencing Sharks

Saili Johri from San Diego State University presented at London Calling 2019 on “Unraveling shark secrets: sequencing genomes and microbiomes for research and conservation.” Johri explained how they are using the MinION to conserve sharks and rays. They emphasized how sharks are apex predators important for oceanic ecosystems and maintaining coral reefs. Sharks make direct […]
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Methods to Study Mitochondrial DNA Variation

Mo Li from King Abdullah University of Science and Technology (KAUST) in Saudi Arabia presented a five-minute session about “Single-cell full-length nanopore sequencing for quantitative variant analysis of native and genome-edited mitochondria.” They explained that human mitochondrial DNA (mtDNA) has a circular genome of 16.5 kb. Mutant mtDNA has an uneven distribution in tissues, and […]
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Rapid- and Ligation-based Sequencing of mtDNA

Andrea Legati from The Foundation of the Carlo BEsta Neurological Institute, IRCCS, Italy, spoke at the Nanopore Community Meeting 2021 on “Mitochondrial DNA analysis by long-read NGS in patients affected by mitochondrial diseases.” Legati spoke about the role of mitochondria in ATP production and metabolites and the significance of mitochondrial DNA (mtDNA) deletions. There are […]
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