signal

Understanding RNA Modifications: Insights from Nanopore Sequencing

Logan Mulroney from the EMBL-EBI in the UK and Italy spoke at the Nanopore Community Meeting in Boston. The title of the session was “A survey of RNA modifications across the human transcriptome by direct RNA nanopore sequencing.” They spoke about RNA modification and their implications in diseases such as cancer. RNA modifications can have […]
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Gbases and Basecallig

Continuing with the Human genome sequencing and analysis Nanopore Learning course, I watched the session entitled “MinKNOW: Live basecalling and output folder structure.” Marta Verdugo, a member of the Technical Services Team with Oxford Nanopore Technologies, introduced the different data types and how MinKNOW processes signals into reads. Each read corresponds to a signal from […]
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The Advantages of POD5

I have been thinking and learning about POD5 files. Tonight, I watched a relevant Nanopore Community Meeting 2022 session by Alex Merry, Instrument Software Fellow at Oxford Nanopore Technologies. The session was entitled “Arrow: pointing the way forward for high-performance nanopore signal handling with POD5.” They began talking about FAST5 files to store signal data […]
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