Nadia Davidson from The Walter and Eliza Hall Institute in Australia presented at London Calling 2025. The intriguing title of the session was "Blessy: enabling differential analysis of phased protein domains." Blessy is a new tool from Davidson's research group. Davidson spoke about the impact of alternative splicing on protein function. Davidson and team used...

Joy Goffena from the University of Washington presented at London Calling 2025. The title of the session was "Variant phasing for antisense oligonucleotide design using adaptive sampling." Goffena explained antisense oligonucleotide (ASO) technology as short DNA or RNA that can bind target RNA to block translation or even modulate splicing. The goal of their work...

I am back from SABER and getting settled. Tonight I watched Lennart Kester from the Princess Maxima Center in The Netherlands present on "Ultra-fast deep-learned classification algorithms for diagnosing pediatric CNS and solid tumors" at London Calling 2025. Kester explained that over the years they have observed an increase in the number of tumor entities,...

Continuing with the KBase Science Session: Data integration to support (or refute) predictions, I watched the session by Paramvir Dehal and team. The title of the session was "Leveraging LLMs to Synthesize and Develop New Questions." They talked about the use of a KBase Research Assistant with the goal of accelerating science by helping...

Tonight I watched another KBase Science Session: Data integration to support (or refute) predictions. "Integrating data to predict functions for gaps in metabolic models" was the title of Bill Nelson's session. Nelson is from the Pacific Northwest National Laboratory. The work was part of two PNNL SFA projects: a soil microbiome project and a persistence...