Year: 2023

Highly Individual Multiplexed Disease Detection

Caroline Koch from the Imperial College London in the UK presented at London Calling 2023 about “Novel screening platform for highly multiplexed biomarker analysis.” Koch is a PH.D. student. They spoke about how humans express diseases differently: we have different genes and live different lives. Koch described the need for individual highly multiplexed platform to […]
Read more

Some of the World’s Largest Conservation Efforts

The London Calling 2023 showcase on conservation included a session entitled “A low-cost, rapid approach to generate non-model genomes for biodiversity and conservation genomics.” Matt Miller Is from Reneco Wildlife Conservation in the United Arab Emirates. They work on conservation and captive breeding. Miller noted that “Reference Genomes are Models.” Miller said that “no genome […]
Read more

Dynamic Adaptive Sampling

Tonight I continued watching the London Calling 2023 Showcase Stage recordings for sessions on targeted sequencing. The speaker was Lukas Weilguny a Ph.D. student from the EMBL-EBI in the UK. The title of the session was “Dynamic, adaptive sampling during nanopore sequencing using Bayesian experimental design.” They worked on a model that takes the sequencing […]
Read more

Sequencing and Assembly of an Endangered Tortoise Genome

Tonight I watched the Oxford Nanopore Technologies (ONT) London Calling 2023 Showcase Stage on Conservation. In this session, Luca Pandolfini from the Italian Institute of Technology in Italy presented “From genome assembly to epigenome characterisation: a nanopore journey in the footsteps of an endangered tortoise.” Pyxis arachnoides is a tiny tortoise that is critically endangered […]
Read more

Medical Mysteries and CRISPR-Cas9 Nanopore Diagnostics

Cecilia C.S. Yeung & Olga Sala-Torra from the Fred Hutchinson Cancer Center presented the session “Potential clinical utility of long-read sequencing in myeloid neoplasms.” They are both clinicians and saw the potential of long-read sequencing for detection of myeloid neoplasms. The assay has the potential to rapid detect cytogenetic aberrations. Sala-Torra spoke about how fusions […]
Read more

A Bed File to Create a Molecular Diagnostic Panel for Germline Cancer Predisposition

Tonight I continued watching the London Calling 2023 targeted sequencing showcase. In the four-minute recording entitled “The potential use of nanopore sequencing for molecular diagnosis of germline cancer predisposition,” Romain Boidot from the Centre Georges-François Leclerc in France spoke about their use of Oxford Nanopore Technologies (ONT) for molecular diagnosis and sequencing. Their current analysis […]
Read more

Clinicians and Bioinformaticians Using Nanopore for Diagnostics

Tonight I watched the London Calling 2023 panel “The future of clinical genomics.” Four panelists were asked several questions. The first was about the role of bioinformaticians in clinical work. One panelist spoke about how clinicians work on the automation and presenting the data. The exchange with bioinformaticians has helped the clinicians make the most […]
Read more

aPOG and Long-read Sequencing

Janessa Laskin from Canada’s Michael Smith Genome Sciences Centre at BC Cancer presented at London Calling 2023 on the “Potential use of nanopore sequencing in clinical cancer genomics.” Laskin is a clinician and medical oncologist. They spoke about the uncertainty of what treatments to select for patients and the idea of personalized medicine. Laskin explained […]
Read more
Press ESC key to close search