Month: September 2024

Enhancing Research with Direct RNA Nanopore Sequencing

Daniel Garalde, Associate Director of Technology Markets with Oxford Nanopore Technologies, introduced the Knowledge Exchange webinar I watched tonight. The title of the Knowledge Exchange is “How direct RNA nanopore sequencing can enhance your research.” Libby Snell, Director of RNA and cDNA Sample Technology, presented an update on the technology. The date of the recording […]
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Exploring EPI2ME: Bioinformatics for Genomic Characterization

Tonight, I continued watching the ONT webinar I started last night, which focused on scalable human genomic characterization with nanopore sequencing. The second speaker was Anthony Doran, Associate Director of Bioinformatics Field Applications with Oxford Nanopore Technologies. Doran’s session was titled “Bioinformatics from beginner to production: EPI2ME, Oxford Nanopore’s data analysis platform.” ONT’s theme this […]
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Understanding Human Variation and Cancer Genomics via EPI2ME

I started watching a core webinar from Oxford Nanopore Technologies (ONT) tonight. Nick Sisneros from ONT facilitated the presentation. The topic was scalable human genomic characterization with nanopore. The first presentation was by Philipp Rescheneder, Senior Director of Applications Bioinformatics at ONT. They described three end-to-end workflows using EPI2ME: the human variation, cancer genomics, and […]
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Empowering Global Surveillance: CDC’s Training Success

I continued watching the “Celebrating a decade of DNA discoveries: 10 years of the MinION in microbiology” ASM Microbe 2024 session. Matthew Keller, a Biologist with the Genomics & Diagnostics division at the Centers for Disease Control, was the last speaker. Keller’s team focuses on sequencing influenza viruses to monitor seasonal dynamics/surveillance. However, Keller noted […]
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Canine Microbiome Analysis at ASM Microbe 2024

The next talk in the session of Oxford Nanopore Technologies at ASM Microbe 2024. Anna Cusco, a postdoctoral researcher from Fudan University. Cusco spoke about pet health and dog microbiomes. Microbiome analysis can be performed with amplicons or whole genome information. They targeted full-length 16S sequencing to obtain genus and species-level information. One concern is […]
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Tonight, I continued watching the Oxford Nanopore Technologies session from ASM Microbe 2024. The title of the session was “Celebrating a decade of DNA discoveries: 10 years of the MinION in microbiology.”Before the second speaker, the live sequencing demo was shown on the screen. The team was sequencing a microbe and had the audience guess […]
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Evolution of MinION Technology in Microbiology: ASM Microbe 2024 Session Insights by Joshua Quick

Today, I watched the beginning of an Oxford Nanopore Technologies special recording. The title is “Celebrating a decade of DNA discoveries: 10 years of the MinION in microbiology.” This session was from June 14th, 2024, at the ASM Microbe meeting. Pomeranz began by introducing the ONT and noting that there have been over 13,000 publications […]
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Real-time Genomic Characterization of Pediatric Acute Leukemia: UNC Research

The second talk in the session I started watching yesterday was by a postdoctoral fellow from UNC. Julie Geyer from the University of North Carolina Chapel Hill School of Medicine described their research. The title of the talk was “Real-time genomic characterization of pediatric acute leukemia using adaptive sampling.” Leukemia is cancer of the blood. […]
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Long-read Sequencing and Structural Variants in Precision Oncology

“Accelerating precision oncology research with nanopore sequencing” is the name of the session I watched tonight. Anna Dysko, Associate Director of Business Development with Oxford Nanopore Technologies, facilitated the discussion on April 8, 2024. Dysko explained how nanopore sequencing works: DNA or RNA is passed through a nanopore thanks to the action of a motor […]
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Methylation Distribution and RNA Sequencing: Insights from Large-Scale Studies

I continued watching the ONT “Empowering comprehensive sequencing at scale” session. The next speaker in this session was Brynja Sigurpalsdottir who spoke about large-scale methylation studies. They spoke about how base calling is used to detect methylation. The team sequenced 7,179 whole blood samples sequenced on 8906 PromethION R9.4 flowcells! Twenty-two samples were sequenced on […]
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