AML

Complex Karyotype Analysis with Nanopore Sequencing

Anna Dolnik from the Charite University Medical Center in Berlin, Germany, presented at London Calling 2019 on “Genomic profiling in acute myeloid leukemia with complex karyotype.” They presented data on the survival of over 5,100 patients with acute myeloid leukemia (AML). The WHO in 2016 revised the classification of AML. A newly diagnosed AML patient, […]
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CRISPR/Cas9 Targeted Enrichment and Whole Genome Sequencing for Personalized Medicine

Anna Dolnik from the Charite University Medicine Berlin in Germany presented at London Calling 2022 “Combined CRISPR/Cas9 targeted enrichment and whole-genome sequencing allows real-time stratification of acute myeloid leukemia (AML).” AML patient stratification, Dolnik explained, relies on identification of copy number and fusion transcripts. Dolnik mentioned they had presented on ONT-based AML systems before at […]
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