antibiotics

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Improving the Rediscovery of Biosynthetic Gene Clusters

Allison Guitor spoke at the Nanopore Community Meeting 2019 on “Harnessing long-read sequencing for antibiotic discovery.” Guitor is from McMaster University in Canada. They noted that antibiotic resistance is on the rise, and there are multidrug-resistant infections. One of the challenges is that bacteria have membranes and mechanisms to remove antibiotics. Guitor shared a timeline […]
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Metagenomics-based Infection Diagnostics

Justin O’Grady, Associate Professor in Medical Microbiology at the University of East Anglia, presented at the Nanopore Community Meeting 2017 on “Rapid metagenomic diagnosis of hospital acquired pneumonia.” They spoke about the “loss” of effective antibiotics because of rising resistance. O’Grady suggests using metagenomics-based infection diagnostics to use narrow-spectrum antibiotics. Nanopore sequencing is useful because […]
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Sequencing Large Environmental Plasmids

Tonight, I was searching for videos for the course I am preparing to teach on portable genome sequencing technologies. I want to discuss the use of long-read sequencing for identifying and characterizing native plasmids. I found an older yet very relevant London Calling 2019 session. Severine Rangama from the University of Warwick presented a short […]
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Targeted Sequencing of Mycobacterium tuberculosis Resistance Genes with Nanopore

“Profiling drug-resistant Mycobacterium tuberculosis with targeted nanopore sequencing” was the title of the sessionn Shannon Murphy from the Wadsworth Center – New York State Department of Health presented at the Nanopore Community Meeting 2022. Murphy spoke about how they are planning on using Nanopore sequencing to address some of the challenges of Mycobacterium tuberculosis (MTB). […]
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