HIV

Decoding HIV Splicing Patterns with Long-Read RNA Sequencing

I watched Christian Gallardo from the Seattle Children’s Research Institute present at the Nanopore Community Meeting tonight. The title of the five-minute session was “Decoding the spliced HIV-1 transcriptome with accurate long-read RNA sequencing.” They described HIV as a retrovirus that infects CD4 T-cells and behaves like a gene upon integration. Gene expression is regulated through splicing. […]
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Phylogenetics and Phylogeography of HIV: Insights from Big Events Research

Tetyana Vasylyeva from the University of California, Irvine, presented at London Calling 2024. The topic was “Informing infectious disease interventions with genomics during big events.” I was curious about the big events! This session was part of the Clinical & Biopharma Day on Friday, May 24, 2024. Vasylyeva studies phylogenetics, phylodynamics, and phylogeography of HIV! […]
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GRAID to Facilitate Technology Transfer and Training

Tonight, I watched the recording of Lucky Ronald Runtuwene from the University of Tokyo in Japan from London Calling 2019. Runtuwene is part of a sequencing core at a university campus. They have several Illumina devices and a PromethION. Their goal is to expedite research in developing countries. They started a collaboration with Indonesia, starting […]
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A Thirty-year Old SIV Sample

“Looking for a needle in a haystack: nanopore sequencing of a new Simian immunodeficiency virus (SIV) from a chacma baboon (Papio usrinus)” is the title of Susan Engelbrecht’s 2019 London Calling session. Engelbrecht, from Stellenbosch University in South Africa, spoke about primate lentiviruses and their “extreme genetic variability.” SIV is a retrovirus about 9 kb […]
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