isoform

Flames and Blaze: Advancing Long-Read scRNA-seq for Brain Development Research

Mike Clark from The University of Melbourne in Australia presented at London Calling 2024 on “Igniting single-cell analysis of full-length RNA isoforms in brain development.” Clark works on RNA isoforms and developing single-cell analysis methods. They noted that almost all human genes express multiple RNA isoforms. Clark emphasized that alternative splicing modifies which exons are […]
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The IsoMix Toolkit for Long-read RNA-seq

Michael Clark from The University of Melbourne in Australia presented at London Calling 2023 the session entitled “Investigating RNA isoform expression using the IsoMix toolkit.” They have created tools for RNA isoform analyses. Clark shared an example of a human gene expressed in multiple RNA isoforms. They explained that alternative isoforms can create RNAs and […]
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Exploring Isoform Diversity

Tonight I watched the Nanopore Community Meeting 2022 session by Alisa MacCalman from the University of Exeter in the UK. The title of the session was “Ultra-deep targeted transcript sequencing identifies isoform diversity across human pancreatic development.” MacCalman spoke about pancreatic development and that most of the knowledge is from mouse models. They are interested […]
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