Katherine Lawrence, from the Machine Learning and Bioinformatics team at Oxford Nanopore Technologies, spoke at the Nanopore Community Meeting on “Bacterial isolate and plasmid sequencing.” Lawrence began by emphasizing the importance of microbes and learning about their sequences. Long reads help assemble bacterial genomes efficiently. Bacterial genome modifications include 4mC, 5mC, and 6mA. Lawrence noted […]
Laura White from the University of Colorado School of Medicine spoke at London Calling 2024. The title of the session was “So many mods in so little time: >45 RNA modifications profiled by direct RNA-Seq.” They began defining the epigenome. It is the complete set of DNA methylation and other modifications. These can promote or […]
The studio interviews at London Calling 2024 I watched tonight focused on clinical and translational applications. Zoe McDougall asked the three interviewees about the highlights of the updates talk. Ewan Birney director of EMBL-EBI in the UK spoke about the quality updates. Justin O’Sullivan from Liggins Institute at the University of Auckland in New Zealand […]
Yufan Fan from Johns Hopkins University presented at the Nanopore Community Meeting in December 2017. I had not watched this session, and the title captured my attention: Bacterial DNA modifications with Nanopore sequencing. This session was short and full of information. Fan spoke about how bacteria can unleash endonucleases to cut foreign DNA. Their own […]
Tonight I continued with the Human genome sequencing and analysis course from Nanopore Learning. I watched the video about MinKNOW Configuration for Kit 14. Bala Periaswamy from the Technical Applications Team spoke about setting up a MinKNOW run. They explained that kit 14 has improvements in the pore and motor enzyme. These changes result in […]
Wouter De Coster from the VIB Center for Molecular Neurology in Belgium presented a session for the Oxford Nanopore Community Meeting 2020 entitled “Allele-specific methylation in human brains.” De Coster is a bioinformatician and started with a quote from Sydney Brenner: “Progress in science depends on new techniques, new discoveries and new ideas, probably in […]







