Nanocompore

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Nanocompore for Signal Comparison

Tommaso Leonardi from the Italian Institute of Technology (IIT) presented a lightning talk at London Calling 2019 on “signal level RNA modifications detection in eukaryotic non-coding RNAs.” Leonardi explained that there are many RNA modifications, and they developed the tool Nanocompore to compare signals from two conditions. It also takes into account replicates. Nanopore also […]
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Methplotlib and the Development of Tools for Allele-specific Methylation in the Human Brain

Wouter De Coster from the VIB Center for Molecular Neurology in Belgium presented a session for the Oxford Nanopore Community Meeting 2020 entitled “Allele-specific methylation in human brains.” De Coster is a bioinformatician and started with a quote from Sydney Brenner: “Progress in science depends on new techniques, new discoveries and new ideas, probably in […]
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Detecting RNA Modifications with Nanocompore

Logan Mulroney from EMBL-EBI and IIT-CGS Italy presented at London Calling 2022 on “Detecting RNA modifications from nanopore ionic current signals.” They spoke about chemical and physical modifications of RNA and how they are “really dynamic.” I did not know there are “eraser” proteins that remove modifications, “writers” that add the modification, and “readers” that […]
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