Kimberley Billingsley from the National Institutes of Health in the USA spoke at London Calling 2025 on “Decoding the genomics of neurodegenerative diseases with large-scale, long-read sequencing.” This session was an update from the CARD Applied Neurogenomics group. Billingsley divided the session into three topics: long-read sequencing, methylation, and RNA sequencing. Billingsley emphasized that current […]
Helen Gunter from the BASE mRNA Facility at the University of Queensland in Australia spoke at London Calling 2024 on “Innovations in mRNA vaccine precision manufacturing.” BASE is the largest mRNA manufacturer in Australia, supplying commercial, government, and academic research labs. The plasmid is amplified, linearized, and used as a template to transcribe the mRNA. […]
Tonight, I watched the London Calling 2024 studio interview about innovations in conservation and RNA in liquid biopsy. Zoe McDougall interviewed three researchers about conservation genomics and the accessibility of the technologies. Mrinalini Wasta from the San Diego Zoe Wildlife Alliance spoke about the challenges of taking samples from outside communities and involving partners. The […]
Tonight, I watched the London Calling 2019 session by Irina Chelysheva from the University of Hamburg in Germany. The session’s title is “Small, modified, and highly structured: the challenge of tRNA sequencing.” Their lab is interested in sequencing tRNA because it is challenging. The major problems for sequencing, Chelysheva noted, include the short length of […]
Tonight I watched the Oxford Nanopore Technologies Knowledge Exchange on “Library Preparation Kits and Methods.” David Stoddart is the Director of Sample Technology and recorded this session on January 30th, 2020. The session was focused on sequencing kits for DNA and RNA. They defined library preparation as “the act of converting sample into format compatible […]
Akelia Wauchope-Odumbo, a Technical Services Manager – Americas with Oxford Nanopore Technologies (ONT), led a Masterclass at London Calling 2023. I watched the recording tonight, as the session title aligns with the course goals for the ONT-based lab I am designing: “How to get started with nanopore sequencing and plan your experiment.” The session started […]
Logan Mulroney from EMBL-EBI and IIT-CGS Italy presented at London Calling 2022 on “Detecting RNA modifications from nanopore ionic current signals.” They spoke about chemical and physical modifications of RNA and how they are “really dynamic.” I did not know there are “eraser” proteins that remove modifications, “writers” that add the modification, and “readers” that […]