Year: 2024

Long-read Sequencing and Structural Variants in Precision Oncology

“Accelerating precision oncology research with nanopore sequencing” is the name of the session I watched tonight. Anna Dysko, Associate Director of Business Development with Oxford Nanopore Technologies, facilitated the discussion on April 8, 2024. Dysko explained how nanopore sequencing works: DNA or RNA is passed through a nanopore thanks to the action of a motor […]
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Methylation Distribution and RNA Sequencing: Insights from Large-Scale Studies

I continued watching the ONT “Empowering comprehensive sequencing at scale” session. The next speaker in this session was Brynja Sigurpalsdottir who spoke about large-scale methylation studies. They spoke about how base calling is used to detect methylation. The team sequenced 7,179 whole blood samples sequenced on 8906 PromethION R9.4 flowcells! Twenty-two samples were sequenced on […]
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Genomics England and ONT

I continued watching a longer session from Oxford Nanopore Technologies (ONT) summer programming tonight. “The era of complete genomes, at any scale” was the title of a session Cora Vaher gave. They talked about how methylation can be detected without additional library preparation. Haplotype-specific methylation could be very useful in learning about genetic diseases. Vaher shared a […]
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Unlocking Genomic Frontiers: ONT’s Long-Read Sequencing Breakthroughs

Tonight I started watching a longer session from Oxford Nanopore Technologies (ONT) summer programming. “The era of complete genomes, at any scale” was the title of a session Cora Vaher gave. They described how long-read sequencing with ONT has changed sequencing. Vaher stated that “the era of full genomes is coming” because there are many […]
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Personalized Medicine for Breast Cancer in the Caribbean: CariGenetics Pilot Study

I wanted to revisit Carika Weldon’s London Calling 2024 session tonight. Weldon founded CariGenetics in Bermuda and has presented in other London Calling sessions. The title of this session was “Towards personalised medicine for breast cancer in the Caribbean: a pilot study.” I wanted to watch this one since I heard about it from the […]
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Next-Generation Sequencing for Tuberculosis Detection: Insights from Findx Scientist

Tonight, I watched a recording on the ONT YouTube channel. Swapna Uplekar, a Principal Scientist in Genomics and Sequencing at Findx presented the session, “Targeted next-generation sequencing for drug-resistant tuberculosis detection.”Uplekar works at Findx to use next-generation sequencing to develop diagnostics for diseases globally. Tuberculosis, Uplekar emphasized, remains the top killer, worsened by COVID-19. Drug-resistant cases often remain […]
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Enhancing PulseNet Surveillance with Long-read Sequencing

Heather Carleton from the Centers for Disease Control & Prevention (CDC) presented at London Calling 2024. The session was titled “Whole-genome sequencing in PulseNet foodborne molecular surveillance systems.” They began discussing the impact of foodborne illness in the United States and globally. Carleton noted that in some cases, hospitalization and death occur. This impact affects […]
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Feasibility of Rapid Respiratory Metagenomic Sequencing for ICU Patients

Gaia Nebbia from the Guy’s and St. Thomas’ NHS Foundation Trust in the UK presented at London Calling 2024. The session focused on respiratory metagenomics in clinical service. This study explored metagenomic sequencing for respiratory infection control and diagnostics. The team identified areas of improvement for the identification of viral sequences. The aim of the […]
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Nanopore Sequencing Applications: Past, Present, and Future Insights with Sissel Juul, VP of Applications

I reached the London Calling 2024 session for the “10 years of nanopore sequencing applications.” Sissel Juul, VP of Applications, spoke about what the technology has enabled. The applications team worked on inspiring the community, showcasing the technology, and driving applications. Now, Juul noted, the team works with the community. Since 2014, the technology has […]
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Public Health Showcase 2024: One Health Genomics and Nanopore Sequencing

Tonight, I watched the London Calling 2024 Public Health Showcase. Associate Director of Global Segment Marketing Aaron Pomerantz helped moderate the session. Lara Urban from Helmholtz AI in Germany was the first speaker. Urban described the connections between One Health Genomics and Nanopore sequencing. One Health Policy was addressed with air microbiome to assess the […]
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