Today, I watched the beginning of an Oxford Nanopore Technologies special recording. The title is “Celebrating a decade of DNA discoveries: 10 years of the MinION in microbiology.” This session was from June 14th, 2024, at the ASM Microbe meeting. Pomeranz began by introducing the ONT and noting that there have been over 13,000 publications […]
“Accelerating precision oncology research with nanopore sequencing” is the name of the session I watched tonight. Anna Dysko, Associate Director of Business Development with Oxford Nanopore Technologies, facilitated the discussion on April 8, 2024. Dysko explained how nanopore sequencing works: DNA or RNA is passed through a nanopore thanks to the action of a motor […]
I continued watching a longer session from Oxford Nanopore Technologies (ONT) summer programming tonight. “The era of complete genomes, at any scale” was the title of a session Cora Vaher gave. They talked about how methylation can be detected without additional library preparation. Haplotype-specific methylation could be very useful in learning about genetic diseases. Vaher shared a […]
Tonight, I watched a recording on the ONT YouTube channel. Swapna Uplekar, a Principal Scientist in Genomics and Sequencing at Findx presented the session, “Targeted next-generation sequencing for drug-resistant tuberculosis detection.”Uplekar works at Findx to use next-generation sequencing to develop diagnostics for diseases globally. Tuberculosis, Uplekar emphasized, remains the top killer, worsened by COVID-19. Drug-resistant cases often remain […]
Thomas R. Kreil from Takeda Austria presented at London Calling 2024. The session title was “Pathogen safety in biopharma: sequencing to come.” Kreil began by noting that they do not want to detect viruses in biopharmaceuticals. For this, they use Adventitious Agent Testing (AAT): they search for cytopathic effects on cells. However, current methods are […]
Alexander Wittenberg from KeyGene in the Netherlands spoke at London Calling 2024 about “Unlocking the banana pangenome: harnessing genetic diversity.” They explained that the genetic diversity of bananas is very low because of the passaging of a single clone. Fusarium wilt and black Sigatoka cause disease and elicit the spraying of large amounts of pesticides. […]
Logan Mulroney from the EMBL-EBI & Center for Genomic Science at the Italian Institute of Technology in Italy presented at London Calling 2024 “A survey of human RNA modifications by direct RNA nanopore sequencing.” Mulroney described RNA modifications as “chemical alterations to canonical nucleotides” and mentioned that they have been implicated in diseases such as […]
Amanda Warr from The Roslin Institute in the UK presented at London Calling 2024 on “What the cat dragged in: emergence of a highly pathogenic feline/canine recombinant coronavirus.” Warr explained that feline coronavirus (FCoV) is common. In a subset of cases, it mutates once in the cat host. This is called feline infectious peritonitis (FIP). […]
The Org. One program is fascinating. I would love to be involved. Tonight, I watched the London Calling 2024 session titled “Org.one to 10.” Kara Dicks, Program Manager at Conservation Genomics with Org.one, spoke about the biodiversity crisis. The Org.one program supports local sequencing. The program has supported over ninety projects. Participants receive kits and […]
The London Calling 2024 studio interview session I watched tonight was about rapid tumor classification. Zoe McDougall spoke to Simon Paine from Nottingham University Hospitals NHS Trust in the UK. Paine is a neuropathologist and analyzes samples to predict patient outcomes. They are excited about discovering ways to classify tumors using Oxford Nanopore Technologies. The […]