Gabrielle Hartley from the University of Connecticut presented at London Calling 2023 a lightning talk. The session’s title is “Telomere-to-telomere nanopore-based genome assembly reveals genomic and epigenetic features of karyotype radiation.” Hartley is a graduate student and is studying the evolution of gibbons. They noted that, unlike other apes, gibbons “have highly rearranged karyotypes concomitant […]
Andrzej A. Benkowski from Eurofins Microbiology Laboratories in Madison, WI, presented at London Calling 2023 a lightning talk on the “Practical uses of nanopore long-read sequencing in a high-throughput contract food laboratory.” They presented a few case studies from the contract lab. The first case study was from a client who experienced an increase in […]
“Single-cell full-length nanopore sequencing for quantitative variant analysis of native and genome-edited mitochondria” is the title of the London Calling 2023 lightning talk I watched tonight. The presenter was Mo Li from King Abdullah University of Science and Technology (KAUST) in Saudi Arabia. Li spoke about the human mitochondrial genome (mtDNA) and the challenges in […]
Caroline Koch from the Imperial College in London, UK, presented at London Calling 2023 a lightning talk on “Novel screening platform for highly multiplexed biomarker analysis.” Koch was a Ph.D. student and explained why we need methods for multiplexed biomarker detection by emphasizing how we all express diseases differently and need sensitive diagnostic methods. They […]
Fei Xiao from the Beijing Hospital in China presented at London Calling 2023 a lightning talk on “Small extrachromosomal circular DNAs as biomarkers for potential pan-cancer diagnosis and prognosis.” Xiao noted that extrachromosomal circular DNA (eccDNA) are circular DNA molecules that are independent of conventional chromosomes and most are smaller than 10 kb. The study […]
I am continuing to watch the London Calling 2023 on-demand lightning talks. Tonight, I watched the session “Discovering the missing variation: a long-read sequencing study into the structural variation in two dairy breeds” by Tuan Viet Nguyen, a research scientist from Agriculture Victoria in Australia. They spoke about structural variants, defined as genomic variants larger […]
I started watching the on-demand lighting talk recordings from London Calling 2023 tonight. I started with Camille Mumm’s session. Mumm is from the University of Michigan and presented on “Exploring the impact of mobile elements on Alzheimer’s disease using targeted long-read sequencing.”Mumm is also a graduate student (at the time of recording). They spoke about […]
Tonight, I watched a recording from the Nanopore Community Meeting 2021 featuring Alexander Wittenberg from KeyGene in the Netherlands. They presented “Accuracy improvements in crop genome assembly using the Q20+ chemistry.” KeyGene is a crop innovation company, and they are generating new tools for genome assembly and structural variant analysis, among other analyses. They built […]
I continue to watch the YouTube “Assembly” playlist from the Oxford Nanopore Technologies (ONT) channel. Tonight, I watched session #8! Ian Henderson from the University of Cambridge in the UK presented at the Nanopore Community Meeting 2021. The session was titled “Assembling the centromeres – the ‘black holes’ of the genome.” Henderson said the centromeres […]
Alaina Shumate from Johns Hopkins University was a speaker at the Nanopore Community Meeting 2021. Shumate was a graduate student and worked on “The annotation of novel genes in a complete human genome.” They noted that in 2003, scientists “finished” the human genome, but reions were still incomplete. In 2021, the Telomere-to-Telomere (T2T) Consortium was […]