sequencing

Tonight, I continued watching the Oxford Nanopore Technologies session from ASM Microbe 2024. The title of the session was “Celebrating a decade of DNA discoveries: 10 years of the MinION in microbiology.”Before the second speaker, the live sequencing demo was shown on the screen. The team was sequencing a microbe and had the audience guess […]
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Real-time Genomic Characterization of Pediatric Acute Leukemia: UNC Research

The second talk in the session I started watching yesterday was by a postdoctoral fellow from UNC. Julie Geyer from the University of North Carolina Chapel Hill School of Medicine described their research. The title of the talk was “Real-time genomic characterization of pediatric acute leukemia using adaptive sampling.” Leukemia is cancer of the blood. […]
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Methylation Distribution and RNA Sequencing: Insights from Large-Scale Studies

I continued watching the ONT “Empowering comprehensive sequencing at scale” session. The next speaker in this session was Brynja Sigurpalsdottir who spoke about large-scale methylation studies. They spoke about how base calling is used to detect methylation. The team sequenced 7,179 whole blood samples sequenced on 8906 PromethION R9.4 flowcells! Twenty-two samples were sequenced on […]
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Unlocking Genomic Frontiers: ONT’s Long-Read Sequencing Breakthroughs

Tonight I started watching a longer session from Oxford Nanopore Technologies (ONT) summer programming. “The era of complete genomes, at any scale” was the title of a session Cora Vaher gave. They described how long-read sequencing with ONT has changed sequencing. Vaher stated that “the era of full genomes is coming” because there are many […]
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Personalized Medicine for Breast Cancer in the Caribbean: CariGenetics Pilot Study

I wanted to revisit Carika Weldon’s London Calling 2024 session tonight. Weldon founded CariGenetics in Bermuda and has presented in other London Calling sessions. The title of this session was “Towards personalised medicine for breast cancer in the Caribbean: a pilot study.” I wanted to watch this one since I heard about it from the […]
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Enhancing PulseNet Surveillance with Long-read Sequencing

Heather Carleton from the Centers for Disease Control & Prevention (CDC) presented at London Calling 2024. The session was titled “Whole-genome sequencing in PulseNet foodborne molecular surveillance systems.” They began discussing the impact of foodborne illness in the United States and globally. Carleton noted that in some cases, hospitalization and death occur. This impact affects […]
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Feasibility of Rapid Respiratory Metagenomic Sequencing for ICU Patients

Gaia Nebbia from the Guy’s and St. Thomas’ NHS Foundation Trust in the UK presented at London Calling 2024. The session focused on respiratory metagenomics in clinical service. This study explored metagenomic sequencing for respiratory infection control and diagnostics. The team identified areas of improvement for the identification of viral sequences. The aim of the […]
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Nanopore Sequencing Applications: Past, Present, and Future Insights with Sissel Juul, VP of Applications

I reached the London Calling 2024 session for the “10 years of nanopore sequencing applications.” Sissel Juul, VP of Applications, spoke about what the technology has enabled. The applications team worked on inspiring the community, showcasing the technology, and driving applications. Now, Juul noted, the team works with the community. Since 2014, the technology has […]
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Public Health Showcase 2024: One Health Genomics and Nanopore Sequencing

Tonight, I watched the London Calling 2024 Public Health Showcase. Associate Director of Global Segment Marketing Aaron Pomerantz helped moderate the session. Lara Urban from Helmholtz AI in Germany was the first speaker. Urban described the connections between One Health Genomics and Nanopore sequencing. One Health Policy was addressed with air microbiome to assess the […]
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Direct Sequencing of Cytosine Modification States from Nanopore Long-Read Data

Dominic Halliwell from the University of Bath in the UK presented at London Calling 2024 on “Direct sequencing of cytosine modification states from nanopore long-read data.” They are a doctoral student and were partially funded by Oxford Nanopore Technologies (ONT). Halliwell spoke about 5mC, 5hmC, and later oxidation derivatives, emphasizing that genome methylation can be […]
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