Guppy

ATCC Insights: Base-Calling in Genomics

David Yarmosh from ATCC presented at the Nanopore Community Meeting in Boston. The session’s title was intriguing: “How good is good enough?” Yarmosh is a bioinformatician with ATCC. They noted that the ATCC was founded in 1925 and now has nearly 5,000 genomes. Yarmosh explained that they are doing about 1,000 genome assemblies per year. […]
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Tonight, I continued watching the Oxford Nanopore Technologies session from ASM Microbe 2024. The title of the session was “Celebrating a decade of DNA discoveries: 10 years of the MinION in microbiology.”Before the second speaker, the live sequencing demo was shown on the screen. The team was sequencing a microbe and had the audience guess […]
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The New Dorado Basecaller is Available!

Mark Bricknell, a Realtime Analysis Fellow with Oxford Nanopore Technologies, spoke at London Calling 2023. The title of the session is “Dorado – the future of basecalling.” I have been thinking about basecalling and duplex reads today. Bricknell explained that basecalling uses recurrent neural networks that are computationally intensive to interpret raw signals into sequences. […]
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At Home Mitogenomes

“Affordable de novo generation of fish mitogenomes using amplification-free targeted enrichment and deep sequencing of long fragments” is the title of the London Calling 2022 session by Ana Ramon-Laca from NOAA Fisheries and the University of Washington that I watched tonight. They began by talking about eDNA surveys and metabarcoding tools to survey environments. Ramon-Laca […]
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